Codex Sinaiticus and Codex Vaticanus, two of the great uncial codices, representatives of the Alexandrian text-type, are considered excellent manuscript witnesses of the text of the New Testament. Most critical editions of the Greek New Testament give precedence to these two chief uncial manuscripts, and the majority of translations are based on their text.
The discovery of P75 proved to be the catalyst for correcting the misconception that early copyists were predominately unskilled. As we elsewhere on our blog earlier, either literate or semi-professional copyist produced the vast majority of the early papyri, and some copied by professionals.
Codex Vaticanus (03, B) contains the Gospels, Acts, the General Epistles, the Pauline Epistles, the Epistle to the Hebrews (up to Hebrews 9:14, καθα[ριει); it lacks 1 and 2 Timothy, Titus, Philemon, and Revelation. It is written on 759 leaves of vellum and is dated to c. 300–325 C.E.