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SECURE AGAINST ATTACKS
 This combination of two Greek negative particles οὐ µή (ou mē) and the aorist subjunctive with reference to a future event is the strongest negation possible in Greek, meaning absolutely not at all, in no way, by no means in any way to something in the future, this being known as the Subjunctive of Emphatic Negation.
Near the end of the year 32 A.D., Jesus Christ sent out seventy disciples to evangelize the Kingdom of God. To the seventy disciples he sent out, Jesus gave them authority over things that could cause injuries, which are represented by serpents and scorpions. (compare Eze 2:6) Again, Jesus is here assuring his seventy followers that by his authority, they will be able to prevail over injurious things, in that, they would symbolically trample on serpents and scorpions. Clearly, Jesus was speaking in symbolic language to the seventy disciples, and by extension, all future disciples, of how they can overcome obstacles in their path if it is according to God’s will and purposes. – Matthew 7:21-23.
Preservation from danger. If you tread on a poisonous reptile that would otherwise injure you, I will keep you from danger. If you go among bitter and malignant enemies that would seek your life, I will preserve you. The scorpion is an animal with eight feet, eight eyes, and a long-jointed tail, ending in a pointed weapon or sting. It is found in tropical climates, and seldom exceeds 4 inches in length. Its sting is extremely poisonous, and it is sometimes fatal to life. It is in Scripture the emblem of malicious and crafty men.
The enemy is Satan. The meaning of this verse is, that Jesus would preserve them from the power of Satan and all his emissaries – from all wicked and crafty men; and this shows that he had divine power. He that can control Satan and his army of demons as well as wicked earthly rulers that can be present to guard against all their machinations, see all their plans, and destroy all their designs, must be clothed with all power and authority that his father had given him. – Matthew 28:18.